PF-3450074 [1352879-65-2]
T16500
CAS Number1352879-65-2
Product group Chemicals
Estimated Purity99.92%
Molecular Weight425.52
Overview
- SupplierTargetMol Chemicals
- Product NamePF-3450074 [1352879-65-2]
- Delivery Days Customer4
- CAS Number1352879-65-2
- CertificationResearch Use Only
- Chemical NamePF-3450074
- Estimated Purity99.92%
- Molecular FormulaC27H27N3O2
- Molecular Weight425.52
- Scientific DescriptionPF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle. PF-3450074 is a specifical inhibitor of HIV-1 capsid protein (CA) and shows a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM).
- Shelf life instruction3 years
- SMILESCN(C(=O)[C@H](Cc1ccccc1)NC(=O)Cc1c(C)[nH]c2ccccc12)c1ccccc1
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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