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PF-3644022 [1276121-88-0]

PF-3644022 [1276121-88-0]

T16501
TargetMol Chemicals
CAS Number1276121-88-0
Product group Chemicals
Estimated Purity99.12%
Molecular Weight374.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PF-3644022 [1276121-88-0]
  • Delivery Days Customer
    4
  • CAS Number
    1276121-88-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PF-3644022
  • Estimated Purity
    99.12%
  • Molecular Formula
    C21H18N4OS
  • Molecular Weight
    374.46
  • Scientific Description
    PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFalpha production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) (IC50s: 53 nM and 5.0 nM, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200