PG 01
M7128
CAS Number853138-65-5
Product group Chemicals
Molecular Weight439.55
Overview
- SupplierAbMole BioScience
- Product NamePG 01
- Delivery Days Customer9
- CAS Number853138-65-5
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC28H29N3O2
- Molecular Weight439.55
- Scientific DescriptionPG 01 is a potent CFTR Cl- channel potentiator.PG01 was effective against E193K, G970R and G551D (CFTR mutants) with Kd values of 0.22 uM, 0.45 uM and 1.94 uM, respectively.PG01 was also effective against ΔF508 (Ka 0.3 uM).PG01 increased ΔF508-CFTR Cl- currents with the addition of Forskolin. F508-CFTR Cl- current after the addition of Forskolin.
- UNSPSC12352200