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PGP9.5 antibody

Research Use Only
GTX109637
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUCHL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PGP9.5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.13 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7345
  • Target name
    UCHL1
  • Target description
    ubiquitin C-terminal hydrolase L1
  • Target synonyms
    epididymis luminal protein 117; epididymis secretory protein Li 53; HEL-117; HEL-S-53; NDGOA; neuron cytoplasmic protein 9.5; PARK5; PGP 9.5; PGP9.5; PGP95; SPG79; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thioesterase L1; ubiquitin thiolesterase; Uch-L1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP09936
  • Protein Name
    Ubiquitin carboxyl-terminal hydrolase isozyme L1
  • Scientific Description
    UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons (Doran et al., 1983 [PubMed 6343558]).[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model. Koshimizu H et al., 2020 Dec 15, Life Sci
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  • Cadmium telluride quantum dot-exposed human bronchial epithelial cells: a further study of the cellular response by proteomics. Xu YM et al., 2019 Nov 1, Toxicol Res (Camb)
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  • Identification of Cardiac Expression Pattern of Transient Receptor Potential Vanilloid Type 1 (TRPV1) Receptor using a Transgenic Reporter Mouse Model. Hong J et al., 2020 Oct 15, Neurosci Lett
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  • Calmangafodipir Reduces Sensory Alterations and Prevents Intraepidermal Nerve Fibers Loss in a Mouse Model of Oxaliplatin Induced Peripheral Neurotoxicity. Canta A et al., 2020 Jul 7, Antioxidants (Basel)
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  • Cholinergic neuroplasticity in asthma driven by TrkB signaling. Dragunas G et al., 2020 Jun, FASEB J
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  • Ameloblastomas Exhibit Stem Cell Potential, Possess Neurotrophic Properties, and Establish Connections with Trigeminal Neurons. Pagella P et al., 2020 Mar 6, Cells
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  • Topiramate prevents oxaliplatin-related axonal hyperexcitability and oxaliplatin induced peripheral neurotoxicity. Alberti P et al., 2020 Mar 1, Neuropharmacology
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  • High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats. Meregalli C et al., 2018 Aug 21, J Neuroinflammation
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  • Na+ /K+ -ATPase coupled to endothelin receptor type B stimulates peripheral nerve regeneration via lactate signalling. Tu NH et al., 2017 Sep, Eur J Neurosci
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