
FACS analysis of 10? Jurkat cells (fixed and permeabilized) in 150microl reaction using GTX10930 PHD2 antibody. Dilution : 3 microg/ml
PHD2 antibody
GTX10930
ApplicationsElectron Microscopy, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetEGLN1
Overview
- SupplierGeneTex
- Product NamePHD2 antibody
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Mouse.
- Application Supplier NoteWB: 1:500 - 1:2500. FACS: 1:10 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsElectron Microscopy, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID54583
- Target nameEGLN1
- Target descriptionegl-9 family hypoxia inducible factor 1
- Target synonymsC1orf12; ECYT3; egl nine homolog 1; egl nine-like protein 1; HALAH; HIFPH2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH2; HPH-2; hypoxia-inducible factor prolyl hydroxylase 2; PHD2; prolyl hydroxylase domain-containing protein 2; SM20; zinc finger MYND domain-containing protein 6; ZMYND6
- HostRabbit
- IsotypeIgG
- Protein IDQ9GZT9
- Protein NameEgl nine homolog 1
- Scientific DescriptionThe protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203