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Western blot analysis of extracts of various cell lines using PHF21A Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using PHF21A Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using PHF21A Polyclonal Antibody at dilution of 1:1000.

PHF21A Polyclonal Antibody

E-AB-61892
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    PHF21A Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
  • UNSPSC
    12352203