Western blot analysis of extracts from JK cells, using PHLDA3 antiobdy.
Western blot analysis of extracts from JK cells, using PHLDA3 antiobdy.
PHLDA3 Antibody
CSB-PA185414
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPHLDA3
Overview
- SupplierCusabio
- Product NamePHLDA3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23612
- Target namePHLDA3
- Target descriptionpleckstrin homology like domain family A member 3
- Target synonymspleckstrin homology-like domain family A member 3; pleckstrin homology-like domain, family A, member 2; TDAG51/Ipl homolog 1; TIH1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5J5
- Protein NamePleckstrin homology-like domain family A member 3
- Scientific Descriptionp53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor. Frank D., Mamm. Genome 10:1150-1159(1999). Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203