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ProductsBack/PHLDA3 Antibody, FITC conjugated

PHLDA3 Antibody, FITC conjugated

Research Use Only
CSB-PA017932LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetPHLDA3
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Overview

  • Supplier
    Cusabio
  • Product Name
    PHLDA3 Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID23612
  • Target name
    PHLDA3
  • Target description
    pleckstrin homology like domain family A member 3
  • Target synonyms
    pleckstrin homology-like domain family A member 3; pleckstrin homology-like domain, family A, member 2; TDAG51/Ipl homolog 1; TIH1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5J5
  • Protein Name
    Pleckstrin homology-like domain family A member 3
  • Scientific Description
    p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203