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ProductsBack/PHLDA3 Antibody, FITC conjugated

PHLDA3 Antibody, FITC conjugated

CSB-PA017932LC01HU

ReactivityHuman

Product group Antibodies

TargetPHLDA3

Overview

Supplier
Cusabio
Product Name
PHLDA3 Antibody, FITC conjugated
Delivery Days Customer
20
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
FITC
Gene ID23612
Target name
PHLDA3
Target description
pleckstrin homology like domain family A member 3
Target synonyms
TIH1, pleckstrin homology-like domain family A member 3, TDAG51/Ipl homolog 1, pleckstrin homology-like domain, family A, member 2
Host
Rabbit
Isotype
IgG
Protein IDQ9Y5J5
Protein Name
Pleckstrin homology-like domain family A member 3
Scientific Description
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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