ProductsBack/Phospho-H2AFX (S139) Antibody

Western Blot Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate All lanes: H2AFX antibody at 1.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 16 kDa Observed band size: 16 kDa

Phospho-H2AFX (S139) Antibody

CSB-PA010097OA139PHHU

ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA

Product group Antibodies

ReactivityHuman

TargetH2AX

Overview

Supplier
Cusabio
Product Name
Phospho-H2AFX (S139) Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3014
Target name
H2AX
Target description
H2A.X variant histone
Target synonyms
H2A.X, H2A/X, H2AFX, histone H2AX, H2A histone family member X, H2AX histone, histone H2A.x
Host
Rabbit
Isotype
IgG
Protein IDP16104
Protein Name
Histone H2AX
Scientific Description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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Phospho-H2AFX (S139) Antibody

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