Phospho IGF1 Receptor Antibody Duo (Total, pY1161)
ARG30240
ReactivityHuman
Product group Antibodies
TargetIGF1R
Overview
- SupplierArigo Biolaboratories
- Product NamePhospho IGF1 Receptor Antibody Duo (Total, pY1161)
- Delivery Days Customer23
- CertificationResearch Use Only
- Gene ID3480
- Target nameIGF1R
- Target descriptioninsulin like growth factor 1 receptor
- Target synonymsCD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2
- Modification TypePhosphorylated
- Scientific DescriptionThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203