
Western blot analysis of extract from 293 cells untreated or treated with insulin using IRS-1(Phospho-Ser312) antibody.
Phospho-IRS1 (Ser312) Antibody
CSB-PA174165
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIRS1
Overview
- SupplierCusabio
- Product NamePhospho-IRS1 (Ser312) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3667
- Target nameIRS1
- Target descriptioninsulin receptor substrate 1
- Target synonymsHIRS-1; insulin receptor substrate 1
- HostRabbit
- IsotypeIgG
- Protein IDP35568
- Protein NameInsulin receptor substrate 1
- Scientific DescriptionMay mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76 Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645 Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97(5): 2355-2360 Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203