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PI-103 (Hydrochloride)

HY-10115A
MedChem Express
CAS Number371935-79-4
Product group Chemicals
Estimated Purity98.55
Molecular Weight384.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PI-103 (Hydrochloride) [371935-79-4]
  • Delivery Days Customer
    10
  • CAS Number
    371935-79-4
  • Estimated Purity
    98.55
  • Molecular Formula
    C19H17ClN4O3
  • Molecular Weight
    384.82
  • Scientific Description
    PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC 50 s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110alpha , p110beta , p110delta , p110gamma , mTORC1 , and mTORC2 . PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy [1] [2] [3] [4] .
  • SMILES
    OC1=CC(C2=NC3=C(OC4=C3C=CC=N4)C(N5CCOCC5)=N2)=CC=C1.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200