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PI-103 Hydrochloride [371935-79-4]

PI-103 Hydrochloride [371935-79-4]

T6143L
TargetMol Chemicals
CAS Number371935-79-4
Product group Chemicals
Molecular Weight384.82
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PI-103 Hydrochloride [371935-79-4]
  • Delivery Days Customer
    14
  • CAS Number
    371935-79-4
  • Certification
    Research Use Only
  • Chemical Name
    PI-103 Hydrochloride
  • Molecular Formula
    C19H17ClN4O3
  • Molecular Weight
    384.82
  • Scientific Description
    PI-103 Hydrochloride is a potent dual inhibitor of PI3K and mTOR, demonstrating inhibitory IC50 values of 8 nM for p110alpha, 88 nM for p110beta, 48 nM for p110delta, 150 nM for p110gamma, 20 nM for mTORC1, and 83 nM for mTORC2, respectively. Additionally, it inhibits DNA-PK with an IC50 of 2 nM and induces autophagy [1] [2] [3] [4].
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200