Piceatannol [10083-24-6]

AdipoGen Life Sciences

Piceatannol

10

10083-24-6

Research Use Only

>98%

C14H12O4

244.3

Chemical. CAS: 10083-24-6. Formula: C14H12O4. MW: 244.3. Synthetic. Originally isolated from Euphorbia lagascae. Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. Neuoprotective. Adipogenesis inhibitor. Promotes glucose uptake, AMPK phosphorylation and GLUT4 translocation. Autophagy inducer - Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K [1-3, 9, 14, 15]. Inhibits the tyrosine phosphorylation of STAT3 and STAT5 [4]. Potent apoptosis inducer [5]. Potent anticancer compound [6, 10, 16, 17]. Suppresses NF-kB activation through IkBalpha kinase inhibition [7]. Activator of human deacetylase SIRT1 (sirtuin 1) [8]. Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties [10, 14, 15, 17, 19]. Neuoprotective [11, 14]. Adipogenesis inhibitor [18]. Promotes glucose uptake, AMPK phosphorylation and GLUT4 translocation [20]. Autophagy inducer [21]

OC1=CC(\C=C\C2=CC=C(O)C(O)=C2)=CC(O)=C1

-20°C,2°C to 8°C

12352200