Picropodophyllin (PPP)

Selleck Chemicals

Picropodophyllin (PPP) [477-47-4]

9

477-47-4

Research Use Only

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Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.

-80°C

51202000