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PIM447 (LGH447) Hydrochloride

S7985
Selleck Chemicals
CAS Number1210608-43-7
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    PIM447 (LGH447) Hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1210608-43-7
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    PIM447 (LGH447) Hydrochloride is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3beta, PKN1, and PKCtau, but at a significantly lower potency with IC50 between 1 and 5 microM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000