PIN1 antibody [3G8]

GeneTex

PIN1 antibody [3G8]

9

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

Western Blot, ELISA

Research Use Only

Monoclonal

3G8

1 mg/ml

Unconjugated

PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

DOD; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; PPIase Pin1; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein interacting with never in mitosis A1; rotamase Pin1; UBL5

Mouse

IgG1

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimers disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203