PKCaeta-IN-1

MedChem Express

PKCaeta-IN-1 [1132609-87-0]

5

1132609-87-0

Research Use Only

99.1

C25H25N7

423.51

PKCaeta-IN-1 is a compound that inhibits PKCaeta and CDK2, showing an IC50 value of 5.18 nM for PKCaeta and 1.04 microM for CDK2, with significant selectivity of 200-fold. PKCaeta-IN-1 can reduce the activity of CDK2 while inhibiting PKCaeta.

CN(CC1)CCN1C2=CC=CC3=C2NC(C4=NNC5=C4C=CC(C6=CC=C(N)C=C6)=C5)=N3

-20°C

12352200