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ICC/IF analysis of methanol-fixed MEF cells using GTX50734 PKM1 antibody.
ICC/IF analysis of methanol-fixed MEF cells using GTX50734 PKM1 antibody.
ICC/IF analysis of methanol-fixed MEF cells using GTX50734 PKM1 antibody.

PKM1 antibody

GTX50734
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetPKM
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Overview

  • Supplier
    GeneTex
  • Product Name
    PKM1 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody was raised against a synthetic peptide corresponding to a region within aa 399-403 of human PKM1 (UniProt #P14618-2). Based on a BLAST result, it is specific for PKM1 and does not cross with PKM2.
  • Application Supplier Note
    WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5315
  • Target name
    PKM
  • Target description
    pyruvate kinase M1/2
  • Target synonyms
    CTHBP; cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; HEL-S-30; OIP3; OPA-interacting protein 3; p58; PK, muscle type; PK3; PKM2; pyruvate kinase 2/3; pyruvate kinase isozymes M1/M2; pyruvate kinase muscle isozyme; pyruvate kinase PKM; pyruvate kinase, muscle; TCB; THBP1; thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; tumor M2-PK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14618
  • Protein Name
    Pyruvate kinase PKM
  • Scientific Description
    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis. Li C et al., 2016 Dec, Cancer Chemother Pharmacol
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