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ProductsBack/Placental Alkaline Phosphatase antibody

Placental Alkaline Phosphatase antibody

Research Use Only
GTX72989
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Rat
TargetALPP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Placental Alkaline Phosphatase antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Reacts with human PLAP specifically as determined by immunodiffusion in an agarose plate.
  • Application Supplier Note
    Immunoblot 1:100-1:500. Immunoprecipitation, Immunohistochemistry 1:50. The optimal conditions should be determined by the individual laboratory. This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 with AutoProbe III (GTX28620). It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID250
  • Target name
    ALPP
  • Target description
    alkaline phosphatase, placental
  • Target synonyms
    alkaline phosphatase Regan isozyme; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; ALPI; glycerophosphatase; IAP; Intestinal alkaline phosphatase; Intestinal-type alkaline phosphatase; PALP; placental alkaline phosphatase 1; PLAP; PLAP-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05187
  • Protein Name
    Alkaline phosphatase, placental type
  • Scientific Description
    The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
  • Reactivity
    Human, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. Kohno T et al., 2020 Oct 21, J Neurosci
    Read more
  • Intra-articularly injected mesenchymal stem cells promote cartilage regeneration, but do not permanently engraft in distant organs. Satue M et al., 2019 Jul 12, Sci Rep
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  • Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model. Zwolanek D et al., 2017 Oct 19, JCI Insight
    Read more
  • Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis. Kohno T et al., 2015 Mar 18, J Neurosci
    Read more