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Placental Alkaline Phosphatase antibody

Name: Placental Alkaline Phosphatase antibody
SKU: GTX72989_G10
Availability: BackOrder

GTX72989

ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetALPP

Overview

Supplier
GeneTex
Product Name
Placental Alkaline Phosphatase antibody
Delivery Days Customer
9
Application Supplier Note
Immunoblot 1:100-1:500. Immunoprecipitation, Immunohistochemistry 1:50. The optimal conditions should be determined by the individual laboratory. This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 with AutoProbe III (GTX28620). It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.
Applications
ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.2 mg/ml
Conjugate
Unconjugated
Gene ID250
Target name
ALPP
Target description
alkaline phosphatase, placental
Target synonyms
ALP, ALPI, IAP, PALP, PLAP, PLAP-1, alkaline phosphatase, placental type, Intestinal alkaline phosphatase, Intestinal-type alkaline phosphatase, alkaline phosphatase Regan isozyme, alkaline phosphomonoesterase, glycerophosphatase, placental alkaline phosphatase 1
Host
Rabbit
Isotype
IgG
Protein IDP05187
Protein Name
Alkaline phosphatase, placental type
Scientific Description
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Kohno T, Ishii K, Hirota Y, et al. Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020,40(43):8248-8261. doi: 10.1523/JNEUROSCI.1907-20.2020
Read this paper
Satué M, Schüler C, Ginner N, et al. Intra-articularly injected mesenchymal stem cells promote cartilage regeneration, but do not permanently engraft in distant organs. Sci Rep. 2019,9(1):10153. doi: 10.1038/s41598-019-46554-5
Read this paper
Zwolanek D, Satué M, Proell V, et al. Tracking mesenchymal stem cell contributions to regeneration in an immunocompetent cartilage regeneration model. JCI Insight. 2017,2(20):pii: 87322. doi: 10.1172/jci.insight.87322.
Read this paper
Kohno T, Honda T, Kubo K, et al. Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis. J Neurosci. 2015,35(11):4776-87. doi: 10.1523/JNEUROSCI.4119-14.2015
Read this paper

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Placental Alkaline Phosphatase antibody

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