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Placental Alkaline Phosphatase antibody [SP15] (ready-to-use)

GTX79434
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetALPP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Placental Alkaline Phosphatase antibody [SP15] (ready-to-use)
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. This antibody is highly specific to PLAP and shows no cross-reaction with
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SP15
  • Conjugate
    Unconjugated
  • Gene ID250
  • Target name
    ALPP
  • Target description
    alkaline phosphatase, placental
  • Target synonyms
    alkaline phosphatase Regan isozyme; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; ALPI; glycerophosphatase; IAP; Intestinal alkaline phosphatase; Intestinal-type alkaline phosphatase; PALP; placental alkaline phosphatase 1; PLAP; PLAP-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05187
  • Protein Name
    Alkaline phosphatase, placental type
  • Scientific Description
    The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina. Zhu P et al., 2019 Aug 7, Mol Neurobiol
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