IHC-P analysis of human seminoma tissue using GTX01925 Placental Alkaline Phosphatase antibody [8A9]. Note the strong membrane and cytoplasmic staining of malignant cells.
IHC-P analysis of human seminoma tissue using GTX01925 Placental Alkaline Phosphatase antibody [8A9]. Note the strong membrane and cytoplasmic staining of malignant cells.
Placental Alkaline Phosphatase antibody [8A9]
GTX01925
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetALPP
Overview
- SupplierGeneTex
- Product NamePlacental Alkaline Phosphatase antibody [8A9]
- Delivery Days Customer9
- Antibody SpecificityImmunohistochemical evidence (in house and published) supports reactivity with PLAP and also with PLAP-like enzyme.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID8A9
- ConjugateUnconjugated
- Gene ID250
- Target nameALPP
- Target descriptionalkaline phosphatase, placental
- Target synonymsalkaline phosphatase Regan isozyme; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; ALPI; glycerophosphatase; IAP; Intestinal alkaline phosphatase; Intestinal-type alkaline phosphatase; PALP; placental alkaline phosphatase 1; PLAP; PLAP-1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203