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PMX-53 [219639-75-5]

M20998
AbMole BioScience
CAS Number219639-75-5
Product group Chemicals
Estimated Puritymore then99.0%
Molecular Weight896.09
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    PMX-53 [219639-75-5]
  • Delivery Days Customer
    7
  • CAS Number
    219639-75-5
  • Certification
    Research Use Only
  • Estimated Purity
    more then99.0%
  • Molecular Formula
    C47H65N11O7
  • Molecular Weight
    896.09
  • Scientific Description
    PMX-53 is a potent CD88 (C5aR) antagonist with an IC50 of 20 nM, it inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation.
  • SMILES
    CC(=O)NC(CC1=CC=CC=C1)C(=O)NC2CCCNC(=O)C(CCCN=C(N)N)NC(=O)C(CC3=C[NH]C4=CC=CC=C34)NC(=O)C(CC5CCCCC5)NC(=O)C6CCCN6C2=O
  • Storage Instruction
    Store at ≤ -20°C, protect from light, dry, sealed
  • UNSPSC
    12161500

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