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ProductsBack/PNK antibody [N1C1]

PNK antibody [N1C1]

GTX107488
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
TargetPNKP
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Overview

  • Supplier
    GeneTex
  • Product Name
    PNK antibody [N1C1]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.73 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11284
  • Target name
    PNKP
  • Target description
    polynucleotide kinase 3'-phosphatase
  • Target synonyms
    AOA4; bifunctional polynucleotide phosphatase/kinase; CMT2B2; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; PNK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96T60
  • Protein Name
    Bifunctional polynucleotide phosphatase/kinase
  • Scientific Description
    This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5 phosphorylation and 3 dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. Valdez BC et al., 2017 Nov, Leuk Lymphoma
    Read more

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