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PNPase antibody

GTX118737
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPNPT1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PNPase antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.84 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID87178
  • Target name
    PNPT1
  • Target description
    polyribonucleotide nucleotidyltransferase 1
  • Target synonyms
    COXPD13, DFNB70, OLD35, PNPASE, SCA25, old-35, polyribonucleotide nucleotidyltransferase 1, mitochondrial, 3'-5' RNA exonuclease OLD35, PNPase 1, PNPase old-35, polynucleotide phosphorylase 1, polynucleotide phosphorylase-like protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8TCS8
  • Protein Name
    Polyribonucleotide nucleotidyltransferase 1, mitochondrial
  • Scientific Description
    PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 [PubMed 12419256]).[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Giosa D, Lombardo D, Musolino C, et al. Mitochondrial DNA is a target of HBV integration. Commun Biol. 2023,6(1):684. doi: 10.1038/s42003-023-05017-4
    Read this paper
  • Wang DD, Guo XE, Modrek AS, et al. Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes. J Biol Chem. 2014,289(24):16727-35. doi: 10.1074/jbc.M113.536540
    Read this paper