POLH Polyclonal Antibody

Reddot Biotech

POLH Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.08 mg/ml

Unconjugated

POLH

DNA polymerase eta

RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, DNA polymerase eta transcript, RAD30 homolog A, polymerase (DNA directed), eta, polymerase (DNA) eta, xeroderma pigmentosum variant type protein

Rabbit

IgG

DNA polymerase eta

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. - This is a POLH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Human, Mouse

-20°C

41116161