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Polycystin 2 antibody

GTX113802
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPKD2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Polycystin 2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5311
  • Target name
    PKD2
  • Target description
    polycystin 2, transient receptor potential cation channel
  • Target synonyms
    APKD2, PC2, PKD4, Pc-2, TRPP2, polycystin-2, autosomal dominant polycystic kidney disease type II protein, polycystic kidney disease 2 (autosomal dominant), transient receptor potential cation channel subfamily P member 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13563
  • Protein Name
    Polycystin-2
  • Scientific Description
    This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Oliveira I, Jacinto R, Pestana S, et al. Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease. Int J Mol Sci. 2021,22(16). doi: 10.3390/ijms22169013
    Read this paper
  • Roxo-Rosa M, Jacinto R, Sampaio P, et al. The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR. Biol Open. 2015,4(11):1356-66. doi: 10.1242/bio.014076
    Read this paper