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PON2 antibody [N1C2]

GTX104061
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPON2
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Overview

  • Supplier
    GeneTex
  • Product Name
    PON2 antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5445
  • Target name
    PON2
  • Target description
    paraoxonase 2
  • Target synonyms
    A-esterase 2; aromatic esterase 2; arylesterase 2; paraoxonase nirs; PON 2; serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ15165
  • Protein Name
    Serum paraoxonase/arylesterase 2
  • Scientific Description
    This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer. Devarajan A et al., 2018 Mar 12, Cell Death Dis
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