PON2 antibody [N1C2]
GTX104061
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPON2
Overview
- SupplierGeneTex
- Product NamePON2 antibody [N1C2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5445
- Target namePON2
- Target descriptionparaoxonase 2
- Target synonymsA-esterase 2; aromatic esterase 2; arylesterase 2; paraoxonase nirs; PON 2; serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
- HostRabbit
- IsotypeIgG
- Protein IDQ15165
- Protein NameSerum paraoxonase/arylesterase 2
- Scientific DescriptionThis gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer. Devarajan A et al., 2018 Mar 12, Cell Death DisRead more