Ponatinib-d8

Biorbyt

Ponatinib-d8

10

1562993-37-6

Research Use Only

98.00%

C29H27F3N6O

540.61

Ponatinib D8 is a deuterium labeled Ponatinib. Ponatinib is an orally active inhibitor of multi-targeted kinase(Abl, PDGFRalpha, VEGFR2, FGFR1, and Src with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM, respectively).

[2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4cccnn34)cc2C(F)(F)F)C1([2H])[2H]

-20°C

12352200