Poseltinib

MedChem Express

Poseltinib [1353552-97-2]

9

1353552-97-2

Research Use Only

98.08

C26H26N6O3

470.52

Poseltinib (HM71224) is an orally active, selective, irreversible small molecule Bruton tyrosine kinase ( BTK ) inhibitor. With an IC 50 of 1.95 nM. Poseltinib effectively inhibits the signaling mediated by B cell receptors ( BCR ), Fc receptors ( FcR ), and Toll-like receptors ( TLR ). Poseltinib has anti-inflammatory activity and can be used in the research of rheumatoid arthritis [1] [2] [3] .

O=C(C=C)NC1=CC=CC(OC2=C(OC=C3)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1

-20°C,2°C to 8°C

12352200