ProductsBack/PP2A alpha antibody

PP2A alpha antibody

Name: PP2A alpha antibody
SKU: GTX106334_G10
Availability: BackOrder

GTX106334

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetPPP2CA

Overview

Supplier
GeneTex
Product Name
PP2A alpha antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID5515
Target name
PPP2CA
Target description
protein phosphatase 2 catalytic subunit alpha
Target synonyms
NEDLBA; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; protein phosphatase 2, catalytic subunit, alpha isozyme; replication protein C; RP-C; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Host
Rabbit
Isotype
IgG
Protein IDP67775
Protein Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Scientific Description
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

A functional interaction between liprin-alpha1 and B56gamma regulatory subunit of protein phosphatase 2A supports tumor cell motility. Ripamonti M et al., 2022 Sep 28, Commun Biol
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Omalizumab Restores Response to Corticosteroids in Patients with Eosinophilic Chronic Rhinosinusitis and Severe Asthma. Kobayashi Y et al., 2021 Jul 7, Biomedicines
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Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome. Di Domenico F et al., 2019 May, Redox Biol
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CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation. Sheu JR et al., 2018 Feb, J Cell Mol Med
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PMC, a potent hydrophilic alpha-tocopherol derivative, inhibits NF-kappaB activation via PP2A but not IkappaBalpha-dependent signals in vascular smooth muscle cells. Hsieh CY et al., 2014 Jul, J Cell Mol Med
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