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PPAR gamma antibody

Research Use Only
GTX19481
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityBovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
TargetPPARG
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Overview

  • Supplier
    GeneTex
  • Product Name
    PPAR gamma antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    React with PPARgamma1 and PPARgamma2.
  • Application Supplier Note
    WB: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5468
  • Target name
    PPARG
  • Target description
    peroxisome proliferator activated receptor gamma
  • Target synonyms
    CIMT1; GLM1; NR1C3; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor-gamma 5; peroxisome proliferator-activated receptor-gamma splicing; PPARG1; PPARG2; PPARG5; PPARgamma; PPAR-gamma
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP37231
  • Protein Name
    Peroxisome proliferator-activated receptor gamma
  • Scientific Description
    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Magnolol may contribute to barrier function improvement on imiquimod-induced psoriasis-like dermatitis animal model via the downregulation of interleukin-23. Guo JW et al., 2021 May, Exp Ther Med
    Read more
  • Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway. Liu H et al., 2020, Diabetes Metab Syndr Obes
    Read more
  • Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels. Hwang HJ et al., 2018 Nov, J Cell Physiol
    Read more
  • Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1alpha-dependent pathway. Jhuang HJ et al., 2015 Apr 10, Oncotarget
    Read more
  • Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. Ho FM et al., 2012 Jun 26, J Ethnopharmacol
    Read more
  • Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis. Sarruf DA et al., 2009 Feb, Endocrinology
    Read more