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PPAR gamma antibody

GTX19481
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
TargetPPARG
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Overview

  • Supplier
    GeneTex
  • Product Name
    PPAR gamma antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5468
  • Target name
    PPARG
  • Target description
    peroxisome proliferator activated receptor gamma
  • Target synonyms
    CIMT1, FPLD3, GLM1, NR1C3, PPARG1, PPARG2, PPARG5, PPARgamma, peroxisome proliferator-activated receptor gamma, PPAR-gamma, nuclear receptor subfamily 1 group C member 3, peroxisome proliferator-activated receptor-gamma 5, peroxisome proliferator-activated receptor-gamma splicing
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP37231
  • Protein Name
    Peroxisome proliferator-activated receptor gamma
  • Scientific Description
    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

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  • Liu H, Zhan YL, Luo GJ, et al. Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway. Diabetes Metab Syndr Obes. 2020,13:3075-3087. doi: 10.2147/DMSO.S253097
    Read this paper
  • Hwang HJ, Park KS, Choi JH, et al. Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels. J Cell Physiol. 2018,233(11):8701-8710. doi: 10.1002/jcp.26750
    Read this paper
  • Jhuang HJ, Hsu WH, Lin KT, et al. Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway. Oncotarget. 2015,6(10):7788-803.
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  • Ho FM, Liao YH, Yang AJ, et al. Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. J Ethnopharmacol. 2012,142(1):175-87. doi: 10.1016/j.jep.2012.04.034
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  • Sarruf DA, Yu F, Nguyen HT, et al. Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis. Endocrinology. 2009,150(2):707-12. doi: 10.1210/en.2008-0899
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