PPAR gamma antibody
GTX19481
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
TargetPPARG
Overview
- SupplierGeneTex
- Product NamePPAR gamma antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID5468
- Target namePPARG
- Target descriptionperoxisome proliferator activated receptor gamma
- Target synonymsCIMT1, FPLD3, GLM1, NR1C3, PPARG1, PPARG2, PPARG5, PPARgamma, peroxisome proliferator-activated receptor gamma, PPAR-gamma, nuclear receptor subfamily 1 group C member 3, peroxisome proliferator-activated receptor-gamma 5, peroxisome proliferator-activated receptor-gamma splicing
- HostRabbit
- IsotypeIgG
- Protein IDP37231
- Protein NamePeroxisome proliferator-activated receptor gamma
- Scientific DescriptionThis gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Chicken, Hamster, Human, Mouse, Porcine, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Guo JW, Cheng YP, Liu CY, et al. Magnolol may contribute to barrier function improvement on imiquimod-induced psoriasis-like dermatitis animal model via the downregulation of interleukin-23. Exp Ther Med. 2021,21(5):448. doi: 10.3892/etm.2021.9876Read this paper
- Liu H, Zhan YL, Luo GJ, et al. Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway. Diabetes Metab Syndr Obes. 2020,13:3075-3087. doi: 10.2147/DMSO.S253097Read this paper
- Hwang HJ, Park KS, Choi JH, et al. Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels. J Cell Physiol. 2018,233(11):8701-8710. doi: 10.1002/jcp.26750Read this paper
- Jhuang HJ, Hsu WH, Lin KT, et al. Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway. Oncotarget. 2015,6(10):7788-803.Read this paper
- Ho FM, Liao YH, Yang AJ, et al. Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. J Ethnopharmacol. 2012,142(1):175-87. doi: 10.1016/j.jep.2012.04.034Read this paper
- Sarruf DA, Yu F, Nguyen HT, et al. Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis. Endocrinology. 2009,150(2):707-12. doi: 10.1210/en.2008-0899Read this paper




