PPP3CC antibody [N1C1]

GeneTex

PPP3CC antibody [N1C1]

9

WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.55 mg/ml

Unconjugated

PPP3CC

protein phosphatase 3 catalytic subunit gamma

calcineurin, testis-specific catalytic subunit; CALNA3; CAM-PRP catalytic subunit; CNA3; PP2Bgamma; protein phosphatase 3, catalytic subunit, gamma isozyme; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

Rabbit

IgG

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]

Human

-20°C or -80°C,2°C to 8°C

12352203