PR-619

MedChem Express

PR-619 [2645-32-1]

10

2645-32-1

Research Use Only

99.38

C7H5N5S2

223.28

PR-619 is a broad-range and reversible DUB inhibitor with EC 50 s of 3.93, 4.9, 6.86, 7.2, and 8.61 microM for USP4 , USP8 , USP7 , USP2 , and USP5 , respectively. PR-619 induces ER Stress and ER-Stress related apoptosis [1] [2] [3] [4] .

NC1=C(SC#N)C=C(SC#N)C(N)=N1

-20°C,2°C to 8°C

12352200