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IHC-P analysis of human lung tissue using GTX85112 Prealbumin antibody. Working concentration : 2.5 microg/ml
IHC-P analysis of human lung tissue using GTX85112 Prealbumin antibody. Working concentration : 2.5 microg/ml
IHC-P analysis of human lung tissue using GTX85112 Prealbumin antibody. Working concentration : 2.5 microg/ml

Prealbumin antibody

GTX85112
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTTR
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prealbumin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7276
  • Target name
    TTR
  • Target description
    transthyretin
  • Target synonyms
    ATTR; CTS; CTS1; epididymis luminal protein 111; HEL111; HsT2651; PALB; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; transthyretin; TTN
  • Host
    Chicken
  • Isotype
    IgY
  • Protein IDP02766
  • Protein Name
    Transthyretin
  • Scientific Description
    Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinsons disease, schizophrenia, and depression.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells.
    Read more
  • Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. Ciarpella F et al., 2021 Dec 17, iScience
    Read more

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Figure 1. Western blot analysis of Prealbumin using anti-Prealbumin antibody (PB9749). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human placenta tissue lysate, Lane 2: human HCCP tissue lysate. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Prealbumin antigen affinity purified polyclonal antibody (Catalog # PB9749) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Prealbumin at approximately 14 kDa. The expected band size for Prealbumin is at 14 kDa.
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