PRELP antibody

GeneTex

PRELP antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.95 mg/ml

Unconjugated

PRELP

proline and arginine rich end leucine rich repeat protein

55 kDa leucine-rich repeat protein of articular cartilage; MST161; MSTP161; prolargin; prolargin proteoglycan; proline-arginine-rich end leucine-rich repeat protein; SLRR2A

Rabbit

IgG

Prolargin

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Mouse

-20°C or -80°C,2°C to 8°C

12352203