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Prinaberel

HY-14933
MedChem Express
CAS Number524684-52-4
DownloadMSDS
Product group Chemicals
Estimated Purity98.05
Molecular Weight271.24
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Prinaberel [524684-52-4]
  • Delivery Days Customer
    10
  • CAS Number
    524684-52-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.05
  • Molecular Formula
    C15H10FNO3
  • Molecular Weight
    271.24
  • Scientific Description
    Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) beta agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERbeta, respectively. Prinaberel displays >200-fold selectivity for ERbeta over ERalpha. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/beta-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis[1][2][3].
  • SMILES
    OC1=CC(C=C)=C(OC(C2=CC=C(O)C(F)=C2)=N3)C3=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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