GTX22879 at a 1mg/ml concentration staining~23 kDa (mature) and ~28 kDa (pro-peptide)native bovine prion proteinfrom brain (M. oblongata; 100 mg comprising 10% homogenised brain,diluted 1:10 in buffer, 10ml loaded) by Western blot (non-reducing conditions
Prion Protein (PrP) antibody [1E5 / G6]
GTX22879
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityBovine, Human
TargetPRNP
Overview
- SupplierGeneTex
- Product NamePrion Protein (PrP) antibody [1E5 / G6]
- Delivery Days Customer9
- Antibody SpecificityThis antibody detects:Human recombinant prion protein.Bovine recombinant, native and PrPres proteinase K treated prion protein.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1E5 / G6
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID5621
- Target namePRNP
- Target descriptionprion protein
- Target synonymsalternative prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; p27-30; prion-related protein; PRIP; PrP; PrP27-30; PrP33-35C; PrPc
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- ReactivityBovine, Human
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203