PRMT6 antibody, Internal

GeneTex

PRMT6 antibody, Internal

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ChIP Chromatin ImmunoPrecipitation

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

PRMT6

protein arginine methyltransferase 6

HRMT1L6, protein arginine N-methyltransferase 6, HMT1 hnRNP methyltransferase-like 6, heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, histone-arginine N-methyltransferase PRMT6

Rabbit

IgG

Protein arginine N-methyltransferase 6

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]

-20°C or -80°C,2°C to 8°C

12352203