PRMT7 Antibody

Cusabio

PRMT7 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

PRMT7

protein arginine methyltransferase 7

[Myelin basic protein]-arginine N-methyltransferase PRMT7; histone-arginine N-methyltransferase PRMT7; protein arginine N-methyltransferase 7; SBIDDS

Rabbit

IgG

Protein arginine N-methyltransferase 7

Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

Human

-20°C or -80°C

41116161