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Prohibitin 2 antibody

Name: Prohibitin 2 antibody
SKU: GTX102100_G10
Availability: BackOrder

GTX102100

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetPHB2

Overview

Supplier
GeneTex
Product Name
Prohibitin 2 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.66 mg/ml
Conjugate
Unconjugated
Gene ID11331
Target name
PHB2
Target description
prohibitin 2
Target synonyms
BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22, prohibitin-2, B cell receptor associated protein 37, B-cell associated protein, B-cell receptor-associated protein BAP37, D-prohibitin, repressor of estrogen receptor activity
Host
Rabbit
Isotype
IgG
Protein IDQ99623
Protein Name
Prohibitin-2
Scientific Description
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Liu YH, Weng YP, Tsai HY, et al. Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Phytomedicine. 2018,46:184-192. doi: 10.1016/j.phymed.2018.03.037
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Martinez E, Deval C, Jousse C, et al. Methyl donor deficiency in H9c2 cardiomyoblasts induces ER stress as an important part of the proteome response. Int J Biochem Cell Biol. 2015,59:62-72. doi: 10.1016/j.biocel.2014.11.013
Read this paper
Martinez E, Gérard N, Garcia MM, et al. Myocardium proteome remodelling after nutritional deprivation of methyl donors. J Nutr Biochem. 2013,24(7):1241-50. doi: 10.1016/j.jnutbio.2012.09.008
Read this paper