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ProductsBack/Prohibitin 2 antibody

Prohibitin 2 antibody

GTX102100
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPHB2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prohibitin 2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.66 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11331
  • Target name
    PHB2
  • Target description
    prohibitin 2
  • Target synonyms
    B cell receptor associated protein 37; BAP; Bap37; BCAP37; B-cell associated protein; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; p22; PNAS-141; prohibitin-2; REA; repressor of estrogen receptor activity
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99623
  • Protein Name
    Prohibitin-2
  • Scientific Description
    Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, Phytomedicine
    Read more
  • Methyl donor deficiency in H9c2 cardiomyoblasts induces ER stress as an important part of the proteome response. Martinez E et al., 2015 Feb, Int J Biochem Cell Biol
    Read more
  • Myocardium proteome remodelling after nutritional deprivation of methyl donors. Martinez E et al., 2013 Jul, J Nutr Biochem
    Read more