Propargyl-PEG4-acid
ORB1909293
CAS Number1415800-32-6
Product group Chemicals
Estimated Purity98.00%
Molecular Weight260.28
Overview
- SupplierBiorbyt
- Product NamePropargyl-PEG4-acid [1415800-32-6]
- Delivery Days Customer10
- CAS Number1415800-32-6
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC12H20O6
- Molecular Weight260.28
- Scientific DescriptionPropargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].
- SMILESC(OCCOCCOCC#C)COCCC(O)=O
- Storage Instruction-20°C
- UNSPSC12352200