Propargyl-PEG4-acid [1415800-32-6]

TargetMol Chemicals

Propargyl-PEG4-acid [1415800-32-6]

14

1415800-32-6

Chemical

Research Use Only

Propargyl-PEG4-acid

C12H20O6

260.28

Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].

3 years

C(OCCOCCOCC#C)COCCC(O)=O

-20°C

12352200