Bio-Connect

Prostasin antibody [YL11]

GTX02804
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPRSS8
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prostasin antibody [YL11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    YL11
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5652
  • Target name
    PRSS8
  • Target description
    serine protease 8
  • Target synonyms
    CAP1; channel-activating protease 1; channel-activating serine protease 1; prostasin; protease, serine 8
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDQ16651
  • Protein Name
    Prostasin
  • Scientific Description
    This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation. Lai CH et al., 2016, PLoS One
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