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ProductsBack/Prostasin antibody [N1C2]

Prostasin antibody [N1C2]

GTX103976
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human
TargetPRSS8
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prostasin antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5652
  • Target name
    PRSS8
  • Target description
    serine protease 8
  • Target synonyms
    CAP1, PROSTASIN, prostasin, channel-activating protease 1, channel-activating serine protease 1, protease, serine 8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16651
  • Protein Name
    Prostasin
  • Scientific Description
    This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq]
  • Reactivity
    Drosophila, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Higashi T, Saito AC, Fukazawa Y, et al. EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier. J Cell Biol. 2023,222(1). doi: 10.1083/jcb.202204079
    Read this paper
  • Drees L, Königsmann T, Jaspers MHJ, et al. Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis. PLoS Genet. 2019,15(1):e1007882. doi: 10.1371/journal.pgen.1007882
    Read this paper

Datasheet

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