![PROTAC Mcl1 degrader-1 [2163793-38-0] PROTAC Mcl1 degrader-1 [2163793-38-0]](https://www.targetmol.com/group3/M00/02/36/CgoaEGY7LLCEQPJAAAAAALbu1to178.png)
PROTAC Mcl1 degrader-1 [2163793-38-0]
T11975
CAS Number2163793-38-0
Product group Chemicals
Molecular Weight909.84
Overview
- SupplierTargetMol Chemicals
- Product NamePROTAC Mcl1 degrader-1
- Delivery Days Customer9
- CAS Number2163793-38-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NamePROTAC Mcl1 degrader-1
- Molecular FormulaC45H45BrN6O8S
- Molecular Weight909.84
- Scientific DescriptionPROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with microM-range affinity. PROTAC Mcl1 degrader-1, a proteolysis targeting chimera (PROTAC), is a potently and selectively Mcl-1 inhibitor with an IC50 of 0.78 microM.
- Shelf life instruction3 years
- SMILESO=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1
- Storage Instruction-20°C
- UNSPSC51202000