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Proteasome 20S alpha 2 antibody [N1C3]

GTX103620
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPSMA2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Proteasome 20S alpha 2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5683
  • Target name
    PSMA2
  • Target description
    proteasome 20S subunit alpha 2
  • Target synonyms
    HC3, MU, PMSA2, PSC2, proteasome subunit alpha type-2, alpha-2, macropain subunit C3, multicatalytic endopeptidase complex subunit C3, proteasome (prosome, macropain) subunit, alpha type, 2, proteasome component C3, proteasome subunit HC3, proteasome subunit alpha 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP25787
  • Protein Name
    Proteasome subunit alpha type-2
  • Scientific Description
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Taniguchi H, Okamuro S, Koji M, et al. Possible roles of the transcription factor Nrf1 (NFE2L1) in neural homeostasis by regulating the gene expression of deubiquitinating enzymes. Biochem Biophys Res Commun. 2017,484(1):176-183. doi: 10.1016/j.bbrc.2017.01.038
    Read this paper