GTX102290 WB Image
Proteasome 26S S3 antibody [N1N3]
GTX102290
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameProteasome 26S S3 antibody [N1N3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.23 mg/ml
- IsotypeIgG
- Scientific DescriptionThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203