PRX III antibody

GeneTex

PRX III antibody

9

Western Blot

Research Use Only

Polyclonal

Unconjugated

PRDX3

peroxiredoxin 3

antioxidant protein 1; AOP1; AOP-1; epididymis secretory sperm binding protein; HBC189; MER5; peroxiredoxin III; PRO1748; protein MER5 homolog; prx-III; SP-22; thioredoxin-dependent peroxide reductase, mitochondrial; thioredoxin-dependent peroxiredoxin 3

Chicken

IgY

Thioredoxin-dependent peroxide reductase, mitochondrial

Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. This protein is a protein with antioxidant function and is localized in the mitochondrion. This protein shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved. and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation. differentiation. and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203