PS210 [1221962-86-2]

TargetMol Chemicals

PS210 [1221962-86-2]

4

1221962-86-2

Research Use Only

PS210

99.65%

C19H15F3O5

380.31

PS210 is a potent and selective activator of PDK1 (Kd: 3 microM), specifically targeting the PIF-binding pocket of PDK1 without affecting other protein kinases such as S6K, PKB/Akt, or GSK3. Its prodrug, PS423, serves as a substrate-selective inhibitor of PDK1 in cells, inhibiting the phosphorylation and activation of S6K.

3 years

OC(=O)C(C(CC(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1)C(O)=O

-20°C

12352200